A truly special home located on The Charles River! Sited on over an acre and half of beautiful grounds, 45 Islington Road offers sensational views from every room, ultimate privacy, & endless possibilities. Soaring ceilings, stunning light, gorgeous period details. A gracious floorplan features a beautiful & comfortable living room with marble fireplace & water views. An open kitchen with breakfast nook & butler's pantry. Formal dining room leads to a perfect wet bar & cocktail area. A lovely library/home office with built in bookcases. Large mudroom off of the direct entry 2-car garage, and a pretty powder room complete this level. A grand staircase leads to an elegant second floor. Primary suite with fireplace and bath, three additional generous bedrooms plus family bath. A fantastic and sunny second floor family/play room make for easy modern living. Third floor suite for au-pair/secondary office/guest bed/and gym. Easy access to public transport, Pike, 128, Back Bay, and Cambridge.